Berkelium is an artificial actinide element that can only be prepared by irradiating curium or americium targets in high-flux reactors; each worldwide production run is measured in micrograms or even nanograms, and no appreciable quantity can be accumulated. Because it is extremely scarce and highly radioactive, berkelium has no industrial, medical, or consumer use. To this day it serves only as a target material for superheavy-element synthesis (used to bombard targets in the production of heavier elements such as californium and einsteinium) and as a subject of fundamental actinide chemistry research.
Berkelium compounds such as berkelium trichloride (BkCl3) and berkelium dioxide (BkO2) are prepared only in tiny, just-weighable batches in the laboratory, where they are used in actinide valence-state and coordination-chemistry studies; they have no application at any scale.